Key result
Fragmented wide QRS on a 12-lead ECG was highly predictive of myocardial scar (sensitivity 86.8%, specificity 92.5%) and independently associated with mortality (P=0.017).
Why the study?
Does the presence of fragmented wide QRS on a 12-lead ECG predict myocardial scar and mortality in patients with known or suspected coronary artery disease?
Cohort (n=879)
Does the presence of fragmented wide QRS on a 12-lead ECG predict myocardial scar and mortality in patients with known or suspected coronary artery disease?
p-value: p=0.017
Fragmented wide QRS on a standard 12-lead ECG is a highly specific marker for myocardial scar and an independent predictor of mortality in patients with known or suspected coronary artery disease.
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May aid noninvasive scar detection via routine ECG in CAD; hypothesis-generating for mortality risk stratification.
Das et al. (2008) conducted a cohort in Known or suspected coronary artery disease with wide QRS (n=879). Fragmented wide QRS (f-wQRS) was evaluated on Myocardial scar and mortality (p=0.017). Fragmented wide QRS on a 12-lead ECG was highly predictive of myocardial scar (sensitivity 86.8%, specificity 92.5%) and independently associated with mortality (P=0.017).
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