Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 27, 2018The Medicine ForumOpen Access

RGS10 regulates platelet signaling to form smaller, denser thrombi with fully activated platelets.

View Full Paper
Ask AI
Bookmark
Share

Key result

RGS10 serves as an actively regulated node on the platelet signaling network, helping to produce smaller and more densely packed hemostatic thrombi with fully activated platelets.

Authors

PMPeisong MaSGShuchi GuptaSSSara Sampietro

Discussion

Loading...

Member takes

Overview

RGS10 modulation remains preclinical; leaves open whether it alters clinical bleeding or thrombosis risk.

PICO

P
Population
Hemostasis and platelet activation
I
Intervention / Comparator
RGS10
O
Primary Outcome
Platelet signaling and thrombus formation

Cite This Study

Ma et al. (2018) studied Hemostasis and platelet activation. RGS10 was evaluated on Platelet signaling and thrombus formation. RGS10 serves as an actively regulated node on the platelet signaling network, helping to produce smaller and more densely packed hemostatic thrombi with fully activated platelets.

synapsesocial.com/papers/6a0ba9fa4f6759c6fca256b8https://doi.org/10.1182/bloodadvances.2017008508
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1RGS/Gi2α interactions modulate platelet accumulation and thrombus formation at sites of vascular injury2010 · 56 citations
  2. 2RGS10 and RGS18 differentially limit platelet activation, promote platelet production, and prolong platelet survival2020 · 28 citations
  3. 3Modulating platelet reactivity through control of RGS18 availability2015 · 27 citations
  4. 4GRK2 regulates ADP signaling in platelets via P2Y1 and P2Y122022 · 20 citations
  5. 5Histidine‑rich Glycoprotein Modulates Platelet Adhesion and Aggregation by Binding to GPIbα and GPIIb/IIIa2026 · 1 citations