September 24, 2021Journal of Clinical Medicine12 citationsOpen Access
The Common Combination of Aortic Stenosis with Mitral Regurgitation: Diagnostic Insight and Therapeutic Implications in the Modern Era of Advanced Echocardiography and Percutaneous Intervention
Key Result
Advanced echocardiography and multimodality imaging play a central role in the diagnostic framework and personalized treatment of patients with combined aortic stenosis and mitral regurgitation.
Structured PICO
P
Population
Patients with a combination of aortic stenosis (AS) and mitral regurgitation (MR) due to degenerative valvular disease
I
Intervention
Advanced echocardiography, multimodality imaging, transcatheter mitral valve replacement or repair, and transcatheter aortic valve replacement
Highlights the need for personalized treatment strategies using advanced imaging and transcatheter interventions for patients with combined aortic stenosis and mitral regurgitation.
Abstract
The combination of aortic stenosis (AS) and mitral regurgitation (MR) is common in patients with degenerative valvular disease. It is characterized by having complex pathophysiology, leading to potential diagnostic pitfalls. Evidence is scarce in the literature to direct the diagnostic framework and treatment of patients with this particular combination of multiple valvular diseases. In this complex scenario, the appropriate use of advanced echocardiography and multimodality imaging methods plays a central role. Transcatheter mitral valve replacement or repair and transcatheter aortic valve replacement widen the surgical options for valve diseases. Therefore, there is an increasing need to reconsider the function, timing, and mode intervention for patients with a combination of AS with MR towards more personalized treatment.
Cite This Study
Mantovani et al. (2021) conducted a review in Aortic stenosis and mitral regurgitation. Advanced echocardiography and multimodality imaging was evaluated. Advanced echocardiography and multimodality imaging play a central role in the diagnostic framework and personalized treatment of patients with combined aortic stenosis and mitral regurgitation.