Key result
Secondary MR links to adverse cardiovascular outcomes and requires GDMT, surgery, or transcatheter intervention.
Secondary mitral regurgitation is managed with guideline-directed medical therapy, surgery, or transcatheter intervention.
Affirms established management of secondary mitral regurgitation; leaves open optimal selection and long-term comparative effectiveness.
Secondary mitral regurgitation, which results from left ventricular dysfunction or remodeling or atrial disease, is associated with adverse cardiovascular outcomes. Treatment includes guideline-directed medical therapy for heart failure, if present, and in some cases, surgery or transcatheter intervention.
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O’Gara et al. (2020) studied this question. Secondary mitral regurgitation is associated with adverse cardiovascular outcomes and is treated with guideline-directed medical therapy, surgery, or transcatheter intervention.
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