Key result
Twelve-month DSM-IV major depressive episodes were significantly less prevalent among respondents aged 65 and older (2.6%) compared to those aged 18-34 (7.0%) in developed countries.
Cross-Sectional (n=89,750)
Yes
Absolute Event Rate: 2.6% vs 7%
p-value: p=<0.001
The study suggests that the lower prevalence of major depressive episodes in the elderly is not due to confounding with physical disorders, as the association between MDE and physical conditions weakens with age.
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Physical comorbidity unlikely explains lower elderly MDE rates; cross-sectional data leaves mechanisms and practice implications open.
Kessler et al. (2009) conducted a cross-sectional in Major Depressive Episodes (n=89,750). Age ≥ 65 years vs. Age 18-34 years was evaluated on 12-month prevalence of DSM-IV/CIDI MDE in developed countries (p=<0.001). Twelve-month DSM-IV major depressive episodes were significantly less prevalent among respondents aged 65 and older (2.6%) compared to those aged 18-34 (7.0%) in developed countries.
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