Key result
Overall, 10% of adults ≥50 years reported clinically significant depressive symptoms, with chronic pain and incontinence being stronger predictors of depression in men (interaction p<0.00).
Cross-Sectional (n=8,175)
The study identifies age- and gender-specific clinical markers for depression risk in older adults, highlighting that physical illness directly associates with depression only in those aged 65 and older.
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May inform gender-specific depression screening in older adults; leaves open causality and needs prospective validation.
O’Regan et al. (2013) conducted a cross-sectional in depression (n=8,175). Physical illness, chronic pain, and incontinence was evaluated on clinically significant depressive symptoms defined by a score of 16 or greater on the 20-item Centre for Epidemiologic Studies Depression scale (95% CI 9-11). Overall, 10% of adults ≥50 years reported clinically significant depressive symptoms, with chronic pain and incontinence being stronger predictors of depression in men (interaction p<0.00).
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