Key result
Baseline diabetes is linked to lower total and excess weight loss 5 years post-bariatric surgery.
Why the study?
The possible impact of diabetes on the magnitude of weight loss outcomes after bariatric surgery has not been precisely quantified.
Does baseline diabetes reduce the magnitude of weight loss outcomes over 5 years in patients undergoing bariatric surgery for obesity?
Cohort (n=334)
No
Does baseline diabetes reduce the magnitude of weight loss outcomes over 5 years in patients undergoing bariatric surgery for obesity?
p-value: p=0.0023
Patients with diabetes experience significantly less total and excess weight loss over 5 years following bariatric surgery compared to those without diabetes.
Diabetes may attenuate weight loss after bariatric surgery; hypothesis-generating association requiring prospective validation.
OBJECTIVE: For patients with obesity and diabetes, bariatric surgery can lead to the remission of both diseases. However, the possible impact of diabetes on the magnitude of weight loss outcomes after bariatric surgery has not been precisely quantified. RESEARCH DESIGN AND METHODS: Data from Michigan Bariatric Surgery Cohort (MI-BASiC) was extracted to examine the effect of baseline diabetes on weight loss outcomes. Consecutive patients older than 18 years of age undergoing gastric bypass (GB) or sleeve gastrectomy (SG) for obesity at University of Michigan between January 2008 and November 2013 were included. Repeated measures analysis was used to determine if diabetes was a predictor of weight loss outcomes over 5 years postsurgery. RESULTS: , diabetes 108 (32.3%)]. Multivariable repeated measures analysis showed, after adjusting for covariates, that individuals with diabetes had a significantly lower percentage of total (p = .0023) and excess weight loss (p = .0212) compared to individuals without diabetes. CONCLUSIONS: Our data demonstrate that patients with diabetes undergoing bariatric surgery would experience less weight loss than patients without diabetes.
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Luo et al. (2023) conducted a cohort in Obesity and diabetes (n=334). Baseline diabetes vs. No diabetes was evaluated on Percentage of total and excess weight loss (p=0.0023). Baseline diabetes in patients undergoing bariatric surgery was associated with a significantly lower percentage of total (p=0.0023) and excess weight loss (p=0.0212) over 5 years.
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