Why the study?
A consensus definition was needed to facilitate the study of the pathophysiology, clinical impact, potential treatment, and identification of cardiovascular risk in orthostatic hypertension.
Establishes a standardized consensus definition for orthostatic hypertension to facilitate future research and clinical identification of at-risk patients.
Standardizes orthostatic hypertension identification in practice; extends the evidence base for consistent research and trials.
We propose a consensus definition of "an exaggerated orthostatic pressor response" in subjects in whom systolic blood pressure increases ≥ 20 mmHg when going from supine to standing posture. This definition can be extended for seated to standing measurements. We reserve the term "orthostatic hypertension" for when this pressor response leads to an upright systolic blood pressure ≥ 140 mmHg. We believe this consensus definition will help in the study of the pathophysiology, clinical impact, and potential treatment of these entities, and identification of patients who are at greater cardiovascular risk.
No takes yet. Share an insight, caveat, or question.
Jordan et al. (2022) conducted a review in Orthostatic hypertension. Consensus definition of orthostatic hypertension was evaluated. The consensus statement defines an exaggerated orthostatic pressor response as a systolic blood pressure increase of ≥20 mmHg upon standing, and orthostatic hypertension when standing SBP is ≥140 mmHg.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: