Key result
Re-excision plus perioperative radiotherapy improves local control and survival after nonradical soft tissue sarcoma resection.
Why the study?
Nonradical resection (R2) of soft tissue sarcomas has been an emerging issue, and the optimal subsequent management and surgical margins remain debatable.
Does re-excision and adjuvant therapy improve outcomes in patients with soft tissue sarcomas after R2 surgery?
Does re-excision and adjuvant therapy improve outcomes in patients with soft tissue sarcomas after R2 surgery?
Re-excision combined with radiotherapy is the recommended strategy to manage patients after nonradical (R2) resection of soft tissue sarcomas to reduce local recurrence.
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May guide post-R2 management in soft tissue sarcoma; leaves open prospective randomized confirmation.
Chmiel et al. (2024) conducted a review in Soft tissue sarcoma (STS) after nonradical (R2) resection. Re-excision and/or adjuvant radiotherapy was evaluated. Re-excision combined with perioperative radiotherapy is recommended for patients with soft tissue sarcoma following nonradical (R2) resection to improve local control and survival.
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