Key result
This review highlights the paradigm shift in soft tissue sarcoma surgery from radical resections to moderate, function-sparing approaches, questioning the independent prognostic impact of surgical margins.
Why the study?
Do function- and limb-sparing resections combined with radiotherapy provide comparable local control and survival to radical resections in patients with soft tissue sarcomas?
Do function- and limb-sparing resections combined with radiotherapy provide comparable local control and survival to radical resections in patients with soft tissue sarcomas?
This review highlights a paradigm shift in soft tissue sarcoma surgery from radical resections to more moderate, function-sparing approaches, as the independent prognostic impact of surgical margins remains inconsistent.
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May support individualized surgical strategies in extremity STS; leaves open need for prospective validation before practice change.
Harati et al. (2017) conducted a review in Soft tissue sarcomas (STS). Surgical resection margins was evaluated. This review highlights the paradigm shift in soft tissue sarcoma surgery from radical resections to moderate, function-sparing approaches, questioning the independent prognostic impact of surgical margins.
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