Why the study?
Does surgical margin status (R0 vs R1) improve overall survival in patients with soft tissue sarcomas of the distal lower extremities?
Population
120 patients with soft tissue sarcomas of the foot, ankle and lower leg treated surgically between 1999 and…
Comparison
Surgical resection with negative margins (R0) vs Surgical resection with positive margins (R1)
Design
Cohort
Follow-up
median 6.3 years
Authors
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R0 margins were not associated with improved OS; leaves open whether function-sparing close margins suffice in this population.
Does surgical margin status (R0 vs R1) improve overall survival in patients with soft tissue sarcomas of the distal lower extremities?
In patients with soft tissue sarcomas of the distal lower extremities, achieving negative surgical margins did not significantly improve long-term overall survival compared to positive margins, suggesting function-sparing resections with close margins may be adequate.
Harati et al. (2016) studied this question.
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