Key result
Complete surgical excision of malignant fibrous histiocytoma of the extremity resulted in 5-year and 10-year disease-specific survival rates of 65% and 59%, respectively.
Why the study?
What are the prognostic factors and outcomes for patients with malignant fibrous histiocytoma of the extremity undergoing complete surgical excision?
Population
239 patients with malignant fibrous histiocytoma of the extremity treated at a single referral institution
Design
Cohort
Follow-up
Up to 10 years
Authors
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Supports complete excision for extremity MFH in observational data; leaves open optimal adjuvant strategies and high-risk subset management.
Cohort (n=239)
No
What are the prognostic factors and outcomes for patients with malignant fibrous histiocytoma of the extremity undergoing complete surgical excision?
Malignant fibrous histiocytomas of the extremity have a relatively favorable prognosis after complete excision, though size ≥ 5 cm, deep depth, and high grade are unfavorable prognostic factors.
Salo et al. (1999) conducted a cohort in Malignant fibrous histiocytoma of the extremity (n=239). Complete surgical excision was evaluated on Disease specific survival. Complete surgical excision of malignant fibrous histiocytoma of the extremity resulted in 5-year and 10-year disease-specific survival rates of 65% and 59%, respectively.
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