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Identify dysregulated microRNAs associated with the risk and onset timing of bone metastasis in clear-cell renal cell carcinoma.

March 28, 2021CancersOpen Access

MicroRNAs Possibly Involved in the Development of Bone Metastasis in Clear-Cell Renal Cell Carcinoma

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Identify dysregulated microRNAs associated with the risk and onset timing of bone metastasis in clear-cell renal cell carcinoma.
Conducted a retrospective analysis examining microRNA expression patterns in patients with clear-cell renal cell carcinoma.
Evaluated correlations between specific dysregulated microRNAs and the occurrence as well as timing of bone metastasis compared to other metastatic sites.
Expression of miR-23a-3p, miR-27a-3p, miR-20a-5p, and miR-335-3p correlated specifically with earlier onset of bone metastasis relative to metastasis in other organs.
Expression of miR-30b-3p and miR-139-3p correlated with a lower frequency of bone metastasis.

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Implication

Retrospective analysis reveals distinct microRNAs linked to bone metastasis in clear-cell renal cell carcinoma, highlighting novel predictive biomarkers and therapeutic targets.

Cite This Study

Kinget et al. (2021) studied this question.

synapsesocial.com/papers/6a0c720095872b300be8b6f2 https://doi.org/10.3390/cancers13071554

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Implication

Retrospective analysis reveals distinct microRNAs linked to bone metastasis in clear-cell renal cell carcinoma, highlighting novel predictive biomarkers and therapeutic targets.

MicroRNAs Possibly Involved in the Development of Bone Metastasis in Clear-Cell Renal Cell Carcinoma

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Discussion

Implication

Cite This Study

MicroRNAs Possibly Involved in the Development of Bone Metastasis in Clear-Cell Renal Cell Carcinoma

Key Points

Discussion

Implication

Cite This Study

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