Key result
Local therapies integrated with systemic treatments may improve survival in metastatic sarcoma.
Why the study?
To review the evidence regarding local treatments in advanced sarcoma and their integration with systemic therapies as management evolves toward a personalized, multidisciplinary approach.
This review highlights the evolving role of local therapies, such as radiotherapy and surgery, in improving survival for patients with advanced sarcoma when integrated with systemic treatments.
This is the authors' abstract. We don't add key points for this paper.
Management of patients with advanced sarcoma has been evolving in recent decades, from a one-fit-all perspective to a more refined, personalized, and multidisciplinary approach. In parallel, the evolution of local therapies (radiotherapy, surgical and interventional radiology techniques) has contributed to the improvement of survival of patients with advanced sarcoma. In this article, we review the evidence regarding local treatments in advanced sarcoma, as well as its integration with systemic therapies, to provide the reader a wider and deeper perspective on the management of patients with metastatic sarcoma.
Answers are grounded in this paper and cite their sources.
May support local therapy integration in select metastatic sarcoma cases; leaves open need for prospective trials to confirm survival gains.
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Hindi et al. (2023) conducted a review in Metastatic sarcoma. Local therapies (radiotherapy, surgical and interventional radiology) was evaluated. This review discusses the evolving role of local therapies, such as radiotherapy and surgery, and their integration with systemic treatments to improve survival in patients with metastatic sarcoma.
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