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Increased body mass index increases the risk for ischemic stroke in Western and Asian populations, but the relationship with hemorrhagic stroke remains less established.
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Obesity is a major risk factor for stroke. However, several studies have reported a protective effect of obesity on stroke, particularly after a prior cardiovascular event, a phenomenon described as the “obesity paradox” or “reverse epidemiology.”1 No convincing biological evidence explains this paradox. The evidence that increased body mass index (BMI) increases risk for ischemic stroke in Western and Asian populations is strong, but the relationship with hemorrhagic stroke remains less established.
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Rexrode et al. (2016) conducted an editorial in Stroke. Body mass index was evaluated. Increased body mass index increases the risk for ischemic stroke in Western and Asian populations, but the relationship with hemorrhagic stroke remains less established.
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