September 22, 2006Cancer Research
Cancer Stem Cells—Perspectives on Current Status and Future Directions: AACR Workshop on Cancer Stem Cells
Authors
Discussion
Loading...
Member takes
Implication
Expert workshop evaluates cancer stem cell models in tumor progression, highlighting the role of self-renewing cellular subsets in driving malignancy.
Key Points
- To review emerging evidence surrounding the cancer stem cell model and assess how self-renewing cellular subpopulations drive tumor initiation and progression.
- Convened an expert workshop organized by the American Association for Cancer Research (AACR).
- Evaluated preclinical and clinical data regarding small subsets of cancer cells displaying stem-like self-renewal properties.
- Identified that cancer development and progression can be driven by distinct cellular subsets possessing self-renewal capacities analogous to normal stem cells.
- Highlighted the necessity of characterizing cancer stem cell biology to guide novel therapeutic strategies targeting tumor propagation.
Cite This Study
Clarke et al. (2006) studied this question.