Key result
Elevated preprocedural hs-CRP linked to ~57% greater risk of myocardial injury during elective PCI.
Why the study?
Does elevated pre-procedural hs-CRP predict periprocedural myocardial injury in patients undergoing elective PCI?
Population
310 patients with chronic stable angina and unstable angina undergoing elective percutaneous coronary…
Comparison
Elevated pre-procedural hs-CRP (>3 mg/L) vs Normal pre-procedural hs-CRP (<3 mg/L)
Design
Cohort
Follow-up
post-procedural
Authors
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May aid pre-PCI risk stratification; leaves open whether hs-CRP-guided strategies reduce injury.
Observational (n=310)
No
Does elevated pre-procedural hs-CRP predict periprocedural myocardial injury in patients undergoing elective PCI?
Effect estimate: OR 1.57 (95% CI 1.361-1.818)
Absolute Event Rate: 21.2% vs 5.3%
p-value: p=0.001
Elevated pre-procedural hs-CRP is an independent predictor of periprocedural myocardial injury during elective PCI, suggesting its potential utility for risk stratification.
Ahmed et al. (2016) conducted an observational in Chronic stable angina and unstable angina (n=310). Elevated hs-CRP (>3 mg/L) vs. Normal hs-CRP (<3 mg/L) was evaluated on Periprocedural myocardial injury (assessed by CK-MB elevation) (OR 1.57, 95% CI 1.361-1.818, p=0.001). Elevated preprocedural hs-CRP (>3 mg/L) independently predicted periprocedural myocardial injury during elective percutaneous coronary intervention with an OR of 1.57.
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