Key result
Transcripts for α-cardiac and α-skeletal actins are co-expressed in developing heart and somites, serving as early markers for myogenesis in the mouse embryo.
Population
Mouse embryo
Design
Preclinical
Authors
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Early actin markers of myogenesis in mice; leaves open translation to human cardiogenesis.
Cardiac actin transcripts serve as early markers of the myogenic program in vivo, detectable before actual muscle fiber differentiation in mouse embryos.
Sassoon et al. (1988) studied myogenesis in the mouse embryo. cRNA probes for α-cardiac and α-skeletal actin mRNAs was evaluated on Detection of actin transcripts. Transcripts for α-cardiac and α-skeletal actins are co-expressed in developing heart and somites, serving as early markers for myogenesis in the mouse embryo.
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