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September 16, 2015Journal of the American Heart AssociationOpen Access

Causes of Death Following Transcatheter Aortic Valve Replacement: A Systematic Review and Meta‐Analysis

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Why the study?

What are the specific causes of death within and after 30 days following TAVR?

Population

Patients undergoing transcatheter aortic valve replacement (TAVR) from 28 studies

Design

Meta-analysis

Follow-up

within and after 30 days

Key result

Transcatheter aortic valve replacement (TAVR) mortality is evenly balanced, with noncardiovascular causes accounting for 46.4% and 51.6% of deaths within and after 30 days, respectively.

Authors

TXTian‐Yuan XiongYLYanbiao LiaoZZZhen‐Gang Zhao

Discussion

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Overview

Clinicians must address both cardiovascular and noncardiovascular risks like infection post-TAVR; extends evidence on balanced long-term mortality drivers.

Study Design

Type

Meta-Analysis

Structured PICO

What are the specific causes of death within and after 30 days following TAVR?

P
Population
Patients undergoing transcatheter aortic valve replacement (TAVR) from 28 studies
I
Intervention
Transcatheter aortic valve replacement (TAVR)
O
Outcome
Causes of death within and after 30 days following TAVRhard clinical

Cardiovascular and noncardiovascular causes of death are evenly balanced after TAVR, with infection/sepsis and heart failure being the most frequent causes both early and late post-procedure.

Cite This Study

Xiong et al. (2015) conducted a meta-analysis in High surgical risk patients requiring aortic valve replacement. Transcatheter aortic valve replacement (TAVR) was evaluated on Causes of death within and after 30 days following TAVR. Transcatheter aortic valve replacement (TAVR) mortality is evenly balanced, with noncardiovascular causes accounting for 46.4% and 51.6% of deaths within and after 30 days, respectively.

synapsesocial.com/papers/6a0cc8e6a4d785ea81625826https://doi.org/10.1161/jaha.115.002096
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