Key result
A canine experimental model for monocusp aortic valve replacement was devised to enable the study of tissue ingrowth patterns and host-graft interactions in variously treated allografts.
Population
Canine experimental model (dogs)
Design
Preclinical
Authors
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Provides a preclinical platform for allograft optimization; leaves open translation to human aortic valve outcomes.
This study describes a canine experimental model for evaluating host-graft interactions and tissue ingrowth in aortic valve allografts.
Goldstein et al. (1983) studied Aortic valve replacement. Monocusp aortic valve replacement using allografts was evaluated on Tissue ingrowth patterns and host-graft interaction. A canine experimental model for monocusp aortic valve replacement was devised to enable the study of tissue ingrowth patterns and host-graft interactions in variously treated allografts.
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