Key result
Filamin was localized specifically in intermediate filament-actin domains and close to the cell border at the inner surface of plasmalemma-associated plaques in smooth muscle cells.
Filamin localizes to intermediate filament-actin domains in smooth muscle, suggesting it contributes to a distinct cytoskeletal system responsible for smooth muscle tone and slow relaxation.
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Filamin may contribute to smooth muscle tone; hypothesis-generating and should not yet change practice.
Small et al. (1986) studied Smooth muscle. Immunocytochemical methods was evaluated on Localization of filamin. Filamin was localized specifically in intermediate filament-actin domains and close to the cell border at the inner surface of plasmalemma-associated plaques in smooth muscle cells.
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