Key result
Open repair of ruptured AAA carries ~36% in-hospital mortality, driven by postoperative MOF and MI.
Why the study?
Factors affecting perioperative, postoperative, and long-term outcomes in patients undergoing open emergency surgical repair of ruptured abdominal aortic aneurysms needed investigation.
Cohort (n=463)
In patients undergoing open surgical repair for ruptured abdominal aortic aneurysms, mortality remains high and is strongly predicted by operative duration and postoperative complications like multi-organ failure and myocardial infarction.
Mortality after open repair of ruptured AAA remains high; leaves open whether strategies targeting postoperative MOF and MI improve survival.
We investigated factors that affected perioperative, postoperative, and long-term outcomes of patients who underwent open emergency surgical repair of ruptured abdominal aortic aneurysms (RAAA). All patients who underwent open emergency surgical repair from 1990 to 2011 were included (463 patients; 374 [81%] male; mean age 74.7 ± 8.7years). Logistic and Cox regression analyses were performed to explore the association of variables with outcomes. Preoperatively, median (interquartile range) hemoglobin was 11.2 (9.5-12.8) g/dL, and median creatinine level was 140 (112-177) µmol/L. Intraoperatively, the median operative time was 2.25 (2-3) hours, and median estimated blood loss was 1.5 (0.5-3) L; 250 (54%) patients required intraoperative inotropes, and a median of 6 (4-8) units of blood was transfused. Median length of hospital stay was 11 (7-20) days. In-hospital mortality rate was 35.6%, and 5-year mortality was 48%. Age, distance traveled, operation duration, postoperative myocardial infarction (MI), and multi-organ failure (MOF) were predictors of in-hospital mortality and long-term outcome. Additionally, postoperative acute renal failure predicted in-hospital mortality. In patients with RAAA undergoing open surgical repair, the strongest predictors of in-hospital mortality and long-term outcome were postoperative MOF and MI and operative duration.
No takes yet. Share an insight, caveat, or question.
Barakat et al. (2020) conducted a cohort in Ruptured abdominal aortic aneurysms (RAAA) (n=463). Open emergency surgical repair was evaluated on In-hospital mortality. In patients undergoing open surgical repair for ruptured abdominal aortic aneurysms, in-hospital mortality was 35.6% and 5-year mortality was 48%, with postoperative MOF and MI as strong predictors.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: