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February 22, 2007European Journal of Cardio-Thoracic SurgeryOpen Access

Anticoagulation or antiplatelet therapy of bioprosthetic heart valves recipients: an unresolved issue

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Why the study?

What is the optimal antithrombotic protocol (vitamin K antagonist vs antiplatelet therapy) in the early postoperative period after bioprosthetic aortic valve replacement?

Population

Patients receiving bioprosthetic aortic valve replacement

Design

Review

Key result

A precise antithrombotic protocol for the early postoperative period after bioprosthetic aortic valve replacement remains unresolved, with important differences between international guidelines.

Authors

ACAndrea ColliJVJean‐Philippe VerhoyeALAlain Leguerrier

Discussion

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Member takes

Overview

Individualize early antithrombotic therapy after bioprosthetic AVR by patient risk; leaves open the optimal protocol pending dedicated RCTs.

Structured PICO

What is the optimal antithrombotic protocol (vitamin K antagonist vs antiplatelet therapy) in the early postoperative period after bioprosthetic aortic valve replacement?

P
Population
Patients receiving bioprosthetic aortic valve replacement
I
Intervention
Vitamin K antagonist and antiplatelet therapy
O
Outcome
Antithrombotic complications in the early postoperative period

This review highlights the lack of consensus and conflicting guidelines regarding the optimal early antithrombotic management after bioprosthetic aortic valve replacement.

Cite This Study

Colli et al. (2007) conducted a review in Bioprosthetic aortic valve replacement. Vitamin K antagonist or antiplatelet therapy was evaluated. A precise antithrombotic protocol for the early postoperative period after bioprosthetic aortic valve replacement remains unresolved, with important differences between international guidelines.

synapsesocial.com/papers/6a0cfa4bb31ab1d6e01e73a4https://doi.org/10.1016/j.ejcts.2007.02.002
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