Population
Patients with bioprosthetic and mechanical aortic and mitral valves
Design
Review
Key result
Aortic bioprostheses have lower rates of thrombotic and bleeding complications than mechanical valves (2% vs 4%), and mechanical valves have 2-4 times higher rates of fatal events.
Authors
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Mechanical valves are associated with higher rates of fatal thrombotic and bleeding complications compared to bioprostheses, emphasizing the critical role of adequate warfarin anticoagulation.
Mechanical valves are associated with higher rates of fatal thrombotic and bleeding complications compared to bioprostheses, emphasizing the critical role of adequate warfarin anticoagulation.
L. Henry Edmunds (1987) conducted a review in Prosthetic heart valves. Bioprosthetic valves vs. Mechanical valves was evaluated on Thrombotic and bleeding complications. Aortic bioprostheses have lower rates of thrombotic and bleeding complications than mechanical valves (2% vs 4%), and mechanical valves have 2-4 times higher rates of fatal events.
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