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January 1, 2018Cardiology ResearchOpen Access

Bioprosthetic Valve Thrombosis

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Key result

Bioprosthetic valve thrombosis is a major cause of bioprosthetic valve degeneration, but conclusive evidence-based recommendations for its prevention and treatment with anticoagulation are lacking.

Design

Review

Authors

SSSarina SachdevNBNikky BardiaLNLandai Nguyen

Discussion

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Overview

Lack of evidence-based anticoagulation guidance advises against routine practice changes; leaves open optimal prevention strategies for prospective trials.

PICO

P
Population
Bioprosthetic Valve Thrombosis

This review highlights the increasing recognition of bioprosthetic valve thrombosis, especially post-TAVR, and underscores the need for further research to establish optimal antithrombotic strategies.

Limitations

  • Lack of conclusive evidence-based recommendations for anticoagulation following bioprosthetic valve replacement
  • Optimal treatment and prevention of valve thrombosis in TAVR are poorly studied

Cite This Study

Sachdev et al. (2018) conducted a review in Bioprosthetic Valve Thrombosis. Bioprosthetic valve thrombosis is a major cause of bioprosthetic valve degeneration, but conclusive evidence-based recommendations for its prevention and treatment with anticoagulation are lacking.

synapsesocial.com/papers/6a92cbf3fa60aefc093ad634https://doi.org/10.14740/cr789
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Optimising the Haemodynamics of Aortic Valve-in-valve Procedures2017 · 14 citations
  2. 2Early Degeneration of a Bioprosthetic Mitral Valve Complicated by a Large Left Atrial Thrombus2011 · 2 citations
  3. 3Bioprosthetic aortic valve leaflet thrombosis detected by multidetector computed tomography is associated with adverse cerebrovascular events: a meta-analysis of observational studies2018 · 88 citations
  4. 4Bioprostethic mitral valve thrombosis due to oral contraceptive drug use and management with ultra-slow thrombolytic therapy2015 · 4 citations
  5. 5Left atrial thrombosis in an anticoagulated patient after bioprosthetic valve replacement: Report of a case2014 · 3 citations