January 1, 2000Journal of Cardiovascular Electrophysiology
Mapping and Radiofrequency Catheter Ablation of the Three Types of Sustained Monomorphic Ventricular Tachycardia in Nonischemic Heart Disease
Key result
Radiofrequency catheter ablation abolished clinical recurrence of sustained monomorphic ventricular tachycardia in 77% of patients with nonischemic cardiomyopathy over 15 months.
Why the study?
Does catheter radiofrequency ablation prevent clinical recurrence of ventricular tachycardia in patients with nonischemic cardiomyopathy?
Population
26 consecutive patients with nonischemic cardiomyopathy referred for management of recurrent sustained…
Design
Cohort
Follow-up
15 +/- 12 months
Authors
Discussion
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Implication
Supports ablation for VT in nonischemic cardiomyopathy; leaves open need for randomized confirmation.
Key Points
- The study evaluates the mechanisms of sustained monomorphic ventricular tachycardia in patients with nonischemic cardiomyopathy and assesses catheter ablation efficacy.
- A total of 26 patients with nonischemic cardiomyopathy were studied for recurrent ventricular tachycardia.
- Patients underwent mapping and catheter radiofrequency ablation targeting specific ventricular tachycardia mechanisms.
- Follow-up duration averaged 15 months to assess the recurrence of ventricular tachycardia.
- Catheter ablation abolished clinical recurrence of ventricular tachycardia in 20 (77%) of 26 patients.
- VT was not inducible in 8 (53%) of 15 patients with scar-related reentry post-ablation.
- Ablation was successful in all 5 patients with bundle branch reentry and 6 of 7 patients with focal automaticity.
Study Design
Type
Observational (n=26)
Structured PICO
Does catheter radiofrequency ablation prevent clinical recurrence of ventricular tachycardia in patients with nonischemic cardiomyopathy?
P
Population
26 consecutive patients with nonischemic cardiomyopathy referred for management of recurrent sustained monomorphic ventricular tachycardia
I
Intervention
Catheter mapping and radiofrequency ablation
O
Outcome
Clinical recurrence of ventricular tachycardiahard clinical
Catheter radiofrequency ablation is an effective treatment for sustained monomorphic ventricular tachycardia in patients with nonischemic cardiomyopathy, with an overall efficacy of 77%.
Limitations
- Small sample size
- Selected population
Cite This Study
Delacrétaz et al. (2000) conducted an observational in Sustained monomorphic ventricular tachycardia in nonischemic cardiomyopathy (n=26). Radiofrequency catheter ablation was evaluated on Abolition of clinical recurrence of ventricular tachycardia. Radiofrequency catheter ablation abolished clinical recurrence of sustained monomorphic ventricular tachycardia in 77% of patients with nonischemic cardiomyopathy over 15 months.