Key result
Women face 5 to 33-fold less sports-related sudden cardiac death than men.
Why the study?
Sports-related sudden cardiac death occurs 5-33-fold less frequently in women than men despite increasing female sports participation, but the reasons behind this sex difference remain unclear.
Effect estimate: 5-33-fold lower
This review highlights that sports-related sudden cardiac death is significantly less common in women than men, emphasizing the need to understand sex-specific biological differences and channelopathies to improve targeted prevention.
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May warrant sex-specific athlete risk assessment; hypothesis-generating for hormonal and autonomic mechanisms.
Rajan et al. (2021) conducted a review in Sports-related sudden cardiac death (SrSCD). Female sex vs. Male sex was evaluated on Sports-related sudden cardiac death (5-33-fold lower). Sports-related sudden cardiac death occurs 5 to 33-fold less frequently in women than in men, potentially due to sex-specific variations in hormones, blood pressure, and autonomic tone.
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