April 24, 2014Journal of Cardiovascular Electrophysiology
Regional Difference of Optimal Contact Force to Prevent Acute Pulmonary Vein Reconnection During Radiofrequency Catheter Ablation for Atrial Fibrillation
Key result
Lower ablation contact force is linked to acute pulmonary vein reconnection.
- P<0.0001
- n=57
Why the study?
Does the optimal contact force to prevent acute pulmonary vein reconnection vary by region during catheter ablation for atrial fibrillation?
Population
57 consecutive drug-refractory atrial fibrillation patients undergoing initial pulmonary vein isolation
Design
Cohort
Follow-up
acute (>20 minutes after initial PVI)
Authors
Discussion
Loading...
Member takes
Implication
May support higher regional contact force targets to limit reconnection; leaves open whether optimization improves durable isolation.
Study Design
Type
Observational (n=57)
Multicenter
No
Structured PICO
Does the optimal contact force to prevent acute pulmonary vein reconnection vary by region during catheter ablation for atrial fibrillation?
P
Population
57 consecutive drug-refractory atrial fibrillation patients (mean age, 62 ± 11 years; 43 males) undergoing initial pulmonary vein isolation
I
Intervention
Pulmonary vein isolation using the THERMOCOOL® SMARTTOUCH™ catheter with evaluation of contact force
O
Outcome
Acute pulmonary vein reconnection (APVR), defined as time-dependent reconnection >20 minutes after initial PVI and/or reconnection evoked by intravenous adenosine administration (20 mg)surrogate
Main Result
Absolute Event Rate: 7.5% vs 9.9%
p-value: p=< 0.0001
Optimal contact force to prevent acute pulmonary vein reconnection during AF ablation varies significantly depending on the specific peri-pulmonary vein segment, ranging from 10 to 22 g.
Cite This Study
Sotomi et al. (2014) conducted an observational in Atrial fibrillation (n=57). Radiofrequency catheter ablation with contact force sensing was evaluated on Acute pulmonary vein reconnection (APVR) (p=< 0.0001). Contact force at ablation points with acute pulmonary vein reconnection was significantly lower than at points without reconnection (7.5 g vs. 9.9 g; P < 0.0001).