Key result
Arrhythmogenic cardiomyopathy and Brugada syndrome represent a phenotypic spectrum linked to cardiac connexome mutations.
Population
Patients with arrhythmogenic cardiomyopathy and Brugada syndrome
Design
Review
Authors
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May refine overlapping phenotype classification; hypothesis-generating and requires prospective validation before clinical adoption.
Arrhythmogenic cardiomyopathy and Brugada syndrome can be conceptualized as a spectrum of diseases related to mutations affecting the cardiac connexome.
Agulló-Pascual et al. (2014) conducted a review in Arrhythmogenic cardiomyopathy and Brugada syndrome. Arrhythmogenic cardiomyopathy and Brugada syndrome represent a spectrum of manifestations depending on the effect of mutations on the cardiac connexome.
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