December 9, 2011Stroke
Patients With Transient Ischemic Attack With ABCD 2 2 ≥4
Key result
Patients with TIA and an ABCD2 score <4 who had criteria for emergency treatment had a 90-day stroke rate of 3.9%, compared to 3.4% in those with an ABCD2 score ≥4 (P<0.0001).
Why the study?
Does an ABCD2 score <4 safely identify TIA patients who can be evaluated non-emergently compared to those with ABCD2 score ≥4?
Population
1679 patients with definite or possible transient ischemic attack and complete information on ABCD2 score…
Design
Cohort
Follow-up
90 days
Authors
Discussion
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Implication
TIA patients with ABCD2 <4 plus emergency criteria show comparable stroke risk; leaves open whether score safely guides non-emergent evaluation.
Study Design
Type
Cohort (n=1,679)
Structured PICO
Does an ABCD2 score <4 safely identify TIA patients who can be evaluated non-emergently compared to those with ABCD2 score ≥4?
P
Population
1679 patients with definite or possible transient ischemic attack and complete information on ABCD2 score components from the SOS-TIA prospective cohort
I
Intervention
Evaluation and treatment as soon as possible in a transient ischemic attack clinic (87% within 24 hours of first call)
O
Outcome
Stroke at 90 dayshard clinical
Main Result
Absolute Event Rate: 3.9% vs 3.4%
p-value: p=<0.0001
TIA patients with an ABCD2 score <4 but with criteria for emergency treatment have a similar 90-day stroke risk as those with an ABCD2 score ≥4, suggesting all TIA patients should be evaluated without delay.
Cite This Study
Amarenco et al. (2011) conducted a cohort in Transient ischemic attack (n=1,679). ABCD2 score <4 with criteria for emergency treatment vs. ABCD2 score ≥4 was evaluated on Stroke at 90 days (p=<0.0001). Patients with TIA and an ABCD2 score <4 who had criteria for emergency treatment had a 90-day stroke rate of 3.9%, compared to 3.4% in those with an ABCD2 score ≥4 (P<0.0001).