Key result
Postcontrast ventricular T1 >380 ms on CMR is linked to ~50% greater freedom from AF post-ablation.
Why the study?
Does postcontrast ventricular T1 relaxation time on CMR predict freedom from AF after catheter ablation in patients with symptomatic AF?
Population
103 patients undergoing catheter ablation for symptomatic AF (66% paroxysmal AF), mean age 58±10 years.
Comparison
Preprocedure cardiac magnetic resonance imaging… vs Patients with postcontrast ventricular T1 time…
Design
Cohort
Follow-up
mean 15±7 months
Authors
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May aid pre-ablation risk stratification in AF; leaves open prospective validation of clinical utility.
Cohort (n=103)
Does postcontrast ventricular T1 relaxation time on CMR predict freedom from AF after catheter ablation in patients with symptomatic AF?
Absolute Event Rate: 84% vs 56%
p-value: p=0.002
Shorter postcontrast ventricular T1 relaxation time on CMR, indicative of diffuse ventricular fibrosis, is an independent predictor of AF recurrence after catheter ablation.
McLellan et al. (2014) conducted a cohort in Symptomatic atrial fibrillation (n=103). Postcontrast ventricular T1 mapping on CMR vs. T1 time <380 ms was evaluated on Freedom from atrial fibrillation (p=0.002). A postcontrast ventricular T1 time >380 ms on CMR was associated with greater freedom from atrial fibrillation after catheter ablation compared to <380 ms (84% vs 56%; P=0.002).
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