Long-Term Improvement in Left Ventricular Strain After Successful Catheter Ablation for Atrial Fibrillation in Patients With Preserved Left Ventricular Systolic Function
Key result
Successful catheter ablation with maintenance of sinus rhythm significantly improved left ventricular circumferential strain (-18.3% to -20.4%, P<0.001) compared to patients with AF recurrence.
Why the study?
Does successful catheter ablation for atrial fibrillation improve left ventricular strain in patients with preserved left ventricular systolic function?
Population
78 patients with atrial fibrillation and preserved left ventricular ejection fraction undergoing catheter…
Comparison
Successful catheter ablation with maintenance of… vs Unsuccessful catheter ablation with recurrence…
Design
Cohort
Follow-up
13.8+/-4.7 months
Authors
Discussion
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Implication
Strain improvement after successful ablation is hypothesis-generating; leaves open whether it alters outcomes in preserved-EF patients.
Study Design
Type
Cohort (n=78)
Structured PICO
Does successful catheter ablation for atrial fibrillation improve left ventricular strain in patients with preserved left ventricular systolic function?
P
Population
78 patients with atrial fibrillation and preserved left ventricular ejection fraction undergoing catheter ablation
I
Intervention
Successful catheter ablation with maintenance of sinus rhythm
C
Comparator
Unsuccessful catheter ablation with recurrence of atrial fibrillation
O
Outcome
Left ventricular strain (radial, circumferential, and longitudinal) and strain rate assessed by speckle tracking strain imaging at 12-month follow-upsurrogate
Main Result
Absolute Event Rate: -20.4% vs -17.9%
p-value: p=<0.001
Successful catheter ablation for atrial fibrillation that maintains sinus rhythm improves left ventricular circumferential and longitudinal strain in patients with preserved ejection fraction.
Cite This Study
Tops et al. (2009) conducted a cohort in Atrial fibrillation with preserved left ventricular systolic function (n=78). Catheter ablation with maintenance of sinus rhythm vs. Catheter ablation with recurrence of atrial fibrillation was evaluated on Left ventricular strain (radial, circumferential, and longitudinal) and strain rate (p=<0.001). Successful catheter ablation with maintenance of sinus rhythm significantly improved left ventricular circumferential strain (-18.3% to -20.4%, P<0.001) compared to patients with AF recurrence.