Key result
Catheter ablation targeting mid-diastolic potentials terminates sustained VT from a post-infarction RV free wall scar.
Why the study?
Post-infarction scar-related ventricular tachycardia originating from the RV free wall in patients with RV infarction is rare.
Does catheter ablation successfully terminate sustained ventricular tachycardia in a patient with right ventricular infarction after surgery for a giant right coronary artery aneurysm?
Case Report (n=1)
Does catheter ablation successfully terminate sustained ventricular tachycardia in a patient with right ventricular infarction after surgery for a giant right coronary artery aneurysm?
Detailed electrophysiological mapping and catheter ablation can successfully terminate rare scar-related ventricular tachycardia originating from the right ventricular free wall post-infarction.
Supports ablation feasibility in rare post-infarction RV scar VT; leaves open durability, safety, and generalizability.
Background: Post-infarction scar-related ventricular tachycardia (VT) originating from the right ventricular (RV) free wall in patients with RV infarction is rare. Case summary: A 75-year-old Asian male, with a history of RV infarction after surgery for a giant right coronary artery aneurysm, presented with sustained VT with left bundle branch block and inferior axis morphology. The activation mapping during the VT revealed a focal origin initially propagated from the anterior attachment of the RV wall, and mid-diastolic potentials (MDPs) were detected within the RV free wall close to the anterior attachment. At the MDPs recording site, entrainment pacing showed concealed entrainment. The stimulus-QRS interval was equal to the local electrogram-QRS interval. Successful termination of clinical VT was achieved through radiofrequency delivery targeting the MDPs during the VT. Voltage mapping during sinus rhythm (SR) demonstrated a scar area at the RV free wall. Delayed potentials (DPs) during SR were obtained at the zone of MDPs recorded. Additional ablation was performed to eliminate the DPs, resulting in no further inducibility of VT with programmed stimulation. Discussion: The RV free wall infarction can lead to scar-related arrhythmogenesis. Detailed electrophysiological and functional mapping of such scar areas proved effective in terminating VT.
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Watanabe et al. (2025) conducted a case report in Sustained ventricular tachycardia in right ventricular infarction (n=1). Catheter ablation was evaluated on Termination of clinical VT and non-inducibility. Catheter ablation targeting mid-diastolic potentials successfully terminated sustained ventricular tachycardia originating from a right ventricular free wall scar in a patient with prior RV infarction.
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