Key result
IVT before EVT linked to ~167% higher ICH risk in stroke with unruptured aneurysms.
Why the study?
Does the presence of unruptured intracranial aneurysms increase the risk of hemorrhage during endovascular thrombectomy in acute ischemic stroke patients, and does the addition of intravenous thrombolysis affect this risk?
Population
718 acute ischemic stroke patients with large vessel occlusions treated with endovascular thrombectomy…
Comparison
Endovascular thrombectomy combined with… vs Endovascular thrombectomy (EVT) alone
Design
Cohort
Follow-up
3 months
Authors
Loading...
Endovascular thrombectomy appears relatively safe in acute ischemic stroke patients with unruptured intracranial aneurysms, though the addition of intravenous thrombolysis significantly increases the risk of intracranial hemorrhage.
Observational (n=36)
No
Does the presence of unruptured intracranial aneurysms increase the risk of hemorrhage during endovascular thrombectomy in acute ischemic stroke patients, and does the addition of intravenous thrombolysis affect this risk?
Endovascular thrombectomy appears relatively safe in acute ischemic stroke patients with unruptured intracranial aneurysms, though the addition of intravenous thrombolysis significantly increases the risk of intracranial hemorrhage.
Ye et al. (2025) conducted an observational in Acute ischemic stroke with large vessel occlusions and unruptured intracranial aneurysms (n=36). Endovascular thrombectomy (EVT) with intravenous thrombolysis (IVT) vs. EVT alone was evaluated on In-hospital intracranial hemorrhage (ICH) attributable to UIA rupture after EVT. Intravenous thrombolysis before endovascular thrombectomy in stroke patients with unruptured aneurysms increased any intracranial hemorrhage compared to thrombectomy alone (71.4% vs 26.7%, P=0.008).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: