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May 20, 2026American Journal of Respiratory and Critical Care Medicine

C27-04 Bronchiectasis Complicated by Pulmonary Aspergillosis: A Multicenter Study on Prognosis and Risk Factors

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Authors

XSX SuNanjing Drum Tower HospitalJYJ YangSouthern Medical UniversityXWX WangNanjing Drum Tower Hospital

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Implication

Multicenter study shows poorer outcomes for bronchiectasis patients with pulmonary aspergillosis, suggesting key risk factors.

Key Points

  • This study aims to evaluate the prevalence and characteristics of pulmonary aspergillosis in bronchiectasis patients and identify significant risk factors.
  • Reviewed medical records of 899 bronchiectasis patients from four tertiary hospitals.
  • Identified 62 cases of pulmonary aspergillosis, including 11 invasive and 51 chronic cases, compared to 241 controls without aspergillosis.
  • Conducted chest high-resolution computed tomography (HRCT) scans to assess lung abnormalities.
  • Patients with pulmonary aspergillosis had significantly higher rates of exacerbations (P=0.001) and hospitalizations (P=0.001) within the year.
  • The PA group showed greater prevalence of lung consolidation/infiltrates, cavities, nodular shadows, and pleural thickening on HRCT.
  • One-year mortality rate was higher in PA patients (11.3% vs 3.5%) after discharge.

Cite This Study

Su et al. (2026) studied this question.

synapsesocial.com/papers/6a0d4ec0f03e14405aa99faahttps://doi.org/10.1093/ajrccm/aamag162.4407
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Impact of Respiratory Bacterial Findings on Patients with Chronic Pulmonary Aspergillosis2024 · 3 citations
  2. 2C27-03 Prospective Study of Aspergillus IgG and Clinical Outcomes in Patients With Bronchiectasis2026
  3. 3Prevalence and risk factors for chronic pulmonary aspergillosis in chronic obstructive pulmonary disease patients with acute exacerbations2024 · 3 citations
  4. 4ASPERGILLOSIS AND POST-TUBERCULOSIS LUNG DISEASE: A RELEVANT AND NEGLECTED ASSOCIATION2026
  5. 5Occurrence of Chronic Pulmonary Aspergillosis in Pulmonary Tuberculosis: A Hospital-Based Cross-Sectional Study2025