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January 1, 2026RSC AdvancesOpen Access

Development of an AQbD-guided sustainable RP-HPLC method for simultaneous quantification of saracatinib and rapamycin in lipid–polymer hybrid nanocarriers

Mohit Angolkar Sharanya Paramshetti D. Y. Patil Asha Spandana K. M.Riyaz Ali M. Osmani H.V. Gangadharappa Adel Al Fatease Ali H. Alamri Umme Hani

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Key Points

To develop a sustainable RP-HPLC method guided by AQbD for the simultaneous quantification of saracatinib and rapamycin.
Utilized AQbD framework for method development.
Employed RP-HPLC for analysis of samples.
Focused on lipid-polymer hybrid nanocarriers as a delivery system.
Achieved successful simultaneous quantification of saracatinib and rapamycin.
Demonstrated method sustainability and efficiency in analytical processes.

Implication

AQbD-guided sustainable RP-HPLC quantifies saracatinib and rapamycin in lipid-polymer hybrid nanocarriers, suggesting enhanced analytical efficiency.

Abstract

AQbD-guided sustainable RP-HPLC enables simultaneous quantification of saracatinib and rapamycin in lipid–polymer hybrid nanocarriers.

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Cite This Study

Angolkar et al. (2026) studied this question.

synapsesocial.com/papers/6a0d4f4cf03e14405aa9a984 https://doi.org/10.1039/d6ra01901c

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