Development of an AQbD-guided sustainable RP-HPLC method for simultaneous quantification of saracatinib and rapamycin in lipid–polymer hybrid nanocarriers

Key Points

• To develop a sustainable RP-HPLC method guided by AQbD for the simultaneous quantification of saracatinib and rapamycin.
• Utilized AQbD framework for method development.
• Employed RP-HPLC for analysis of samples.
• Focused on lipid-polymer hybrid nanocarriers as a delivery system.
• Achieved successful simultaneous quantification of saracatinib and rapamycin.
• Demonstrated method sustainability and efficiency in analytical processes.