What question did this study set out to answer?

This case aims to illustrate the occurrence of methotrexate-induced pneumonitis in patients with rheumatoid arthritis and the need for prompt diagnosis.

May 20, 2026American Journal of Respiratory and Critical Care Medicine

C42-49 When Treatment Becomes the Trigger: A Case of Methotrexate-induced Pneumonitis in Rheumatoid Arthritis

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CEC ErbGlobal Water Partnership MMM MinaGlobal Water Partnership BBB ButlerCarilion Clinic

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Implication

Case report presents methotrexate-induced pneumonitis in a patient with rheumatoid arthritis, suggesting early recognition is vital.

Key Points

This case aims to illustrate the occurrence of methotrexate-induced pneumonitis in patients with rheumatoid arthritis and the need for prompt diagnosis.
Presented a case of a 76-year-old male with worsening respiratory symptoms after methotrexate initiation for RA.
Conducted imaging (CT scan) and lab tests to rule out infections and assess lung conditions.
Observed improvement after discontinuing methotrexate and starting steroid therapy.
The patient developed worsening cough and dyspnea following methotrexate therapy for RA.
Imaging revealed fibrotic changes and ground glass opacities, indicating pneumonitis.
Symptoms improved after methotrexate discontinuation and initiation of steroids.

Cite This Study

Erb et al. (2026) studied this question.

synapsesocial.com/papers/6a0d50dcf03e14405aa9d0d5 https://doi.org/10.1093/ajrccm/aamag162.3021

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C42-49 When Treatment Becomes the Trigger: A Case of Methotrexate-induced Pneumonitis in Rheumatoid Arthritis

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Key Points

Cite This Study

C42-49 When Treatment Becomes the Trigger: A Case of Methotrexate-induced Pneumonitis in Rheumatoid Arthritis

Discussion

Member takes

Implication

Key Points

Cite This Study

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