Key result
This review summarizes the genetics, molecular biology, and biochemical properties of mammalian myosin heavy chains, highlighting their role in striated muscle contraction and familial hypertrophic cardiomyopathy.
Population
Mammalian striated muscle and myosin heavy chain (MYH) genes
Design
Review
Authors
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Updates myosin genetics framework for HCM evaluation; leaves open mutation-specific therapeutic validation.
This review summarizes the genetics, molecular biology, and biochemical properties of mammalian myosin heavy chains, highlighting their role in striated muscle contraction and familial hypertrophic cardiomyopathy.
Weiss et al. (1996) conducted a review in Familial hypertrophic cardiomyopathy. Mammalian myosin heavy chain (MYH) genes was evaluated. This review summarizes the genetics, molecular biology, and biochemical properties of mammalian myosin heavy chains, highlighting their role in striated muscle contraction and familial hypertrophic cardiomyopathy.
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