Key result
Sarcomeric myosin heavy chain genes in the rat display tissue-specific and developmentally regulated expression patterns that can be modulated in highly different modes by thyroid hormone.
This study highlights the complex, tissue-specific, and developmentally regulated expression of sarcomeric myosin heavy chain genes and their differential modulation by thyroid hormone.
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Rat myosin data warrant no clinical change in thyroid management; leaves open human translational relevance for cardiac gene regulation.
Mahdavi et al. (1986) reported a review. Sarcomeric myosin heavy chain genes in the rat display tissue-specific and developmentally regulated expression patterns that can be modulated in highly different modes by thyroid hormone.
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