Demonstrates an efficient spiroannulation method in organic synthesis, suggesting broad applications.
A simple, convenient and efficient method for the spiroannulation of 2‐arylindole‐3‐carbaldehydes and 2‐arylquinazolinones with 1,4‐quinones has been reported. The protocol tolerates a wide range of functional groups and the spirocyclic frameworks are isolated in moderate‐to‐good yields. A plausible mechanism is also described for this protocol.
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Raja et al. (2026) studied this question.
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