Reports selective spirocyclization of 4-arylquinazolinones with propargylic alcohols, suggesting efficient synthesis methods for complex compounds.
Ru(II)‐catalyzed oxidative CH activation/annulation of 4‐arylquinazolinones with propargylic alcohol derivatives has been developed for the regioselective construction of 3‐phenyl‐2‐(prop‐1‐en‐2‐yl)‐l’ H ‐spiro[indene‐1,4′quinazolin]‐2′(3′ H )‐one frameworks in high yields with wide functional group tolerance.
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Karthik et al. (2026) studied this question.
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