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January 1, 2025Organic & Biomolecular Chemistry

Ruthenium-Catalyzed Late-Stage C–H Alkenylation of N-arylpyridazino[4,5-b] quinolin-1(2H)-ones

Chinnagounder Kameshwaran Fazlur Rahman Nawaz Khan

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Abstract

A ruthenium-catalyzed one-pot sequential cascade has been developed for the synthesis of functionalized pyridazino[4,5-b]quinolin-1(2H)-ones. The sequence comprises Ru/Cu-catalyzed C(sp3)–H oxidation, cyclization with hydrazine hydrate, Chan–Lam N–H arylation, and Ru/Cu-mediated ortho-selective...

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Cite This Study

Kameshwaran et al. (2025) studied this question.

synapsesocial.com/papers/692b9d9a1d383f2b2a37a0c5 https://doi.org/10.1039/d5ob01511a

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