Key result
The membrane potential of rabbit main pulmonary artery smooth muscle cells is -57 mV, and noradrenaline evokes contraction without depolarizing the membrane at low concentrations.
Population
Smooth muscle cells of the rabbit main pulmonary artery
Comparison
Exposure to tetraethylammonium, procaine… vs Baseline/steady-state conditions
Design
Preclinical
Authors
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Defines rabbit pulmonary artery smooth muscle electrophysiology; hypothesis-generating for vascular models, with no clinical implications yet.
This preclinical study defines the baseline electrophysiological properties and ion flux dynamics of rabbit pulmonary artery smooth muscle cells, classifying them as single-unit type.
Casteels et al. (1977) studied Rabbit main pulmonary artery smooth muscle cells. Tetraethylammonium, procaine, noradrenaline, ouabain, ion-free solutions was evaluated on Membrane potential, length constant, time constant, and ion fluxes. The membrane potential of rabbit main pulmonary artery smooth muscle cells is -57 mV, and noradrenaline evokes contraction without depolarizing the membrane at low concentrations.
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