Key result
Readmission of potassium to K-depleted guinea-pig taenia coli smooth muscle cells demonstrates the existence of an electrogenic sodium pump during stimulation.
Population
Guinea-pig taenia coli smooth muscle cells (K-depleted tissues)
Comparison
Readmission of 5.9 mM-K after complete… vs K-depleted state or normal Krebs solution
Design
Preclinical
Authors
Loading...
Does not inform clinical practice; extends evidence for electrogenic Na pumps to non-cardiac smooth muscle.
The study demonstrates the existence of an electrogenic sodium pump in smooth muscle cells of the guinea-pig taenia coli.
Casteels et al. (1971) studied Guinea-pig taenia coli smooth muscle cells. Potassium readmission after depletion vs. Ouabain, propionate solution, hypertonic solution, altered K concentration, altered temperature was evaluated on Changes of membrane potential, K equilibrium potential, and membrane conductance. Readmission of potassium to K-depleted guinea-pig taenia coli smooth muscle cells demonstrates the existence of an electrogenic sodium pump during stimulation.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: