Population
Guinea-pig stomach circular muscle
Comparison
Alteration of extracellular sodium, potassium… vs Normal extracellular ion concentrations
Design
Preclinical
Authors
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May warrant caution extrapolating Na-K pump roles to human gastric motility; leaves open Ca-Na-K metabolic mechanisms for translational study.
Demonstrates that slow wave generation in guinea-pig stomach circular muscle is regulated by calcium, sodium, and potassium ions through a mechanism independent of the direct action of the Na-K pump.
Ohba et al. (1977) studied this question.
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