Adolescent BMI and early-onset type 2 diabetes among Ethiopian immigrants and their descendants: a nationwide study

In brief: The impact of immigration on the risk of early-onset T2DM (before age 40 years) was assessed in a nationwide cohort. Data on 93 806 native Israelis and 27 684 Israelis of Ethiopian origin, assessed at a mean age 17.5 years, were linked to the Israeli National Diabetes Registry. After adjustment for sociodemographic confounders, the hazard ratios for T2DM among Ethiopian men with normal and high BMI were 3.4 (2.3–5.1) and 15.8 (8.3–30.3), respectively, compared to third-generation Israelis with normal BMI. When the analysis was limited to Israeli-born Ethiopian men, the hazard ratios increased to 4.4 (1.7–11.4) and 29.1 (12.9–70.6), respectively.