Key result
Aortic valve replacement in patients with LVEF <40% demonstrated low perioperative mortality (2.3%) and favorable long-term overall survival of 55% at 10 years.
Why the study?
Does aortic valve replacement provide safe and durable outcomes in patients with severe aortic valve disease and LVEF < 40%?
Cohort (n=132)
Does aortic valve replacement provide safe and durable outcomes in patients with severe aortic valve disease and LVEF < 40%?
Aortic valve replacement in patients with severe aortic valve disease and LVEF < 40% is associated with low perioperative mortality and excellent long-term survival.
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Supports AVR consideration in low-LVEF patients; leaves open need for RCTs to confirm benefit.
Chukwuemeka et al. (2006) conducted a cohort in Aortic valve disease with left ventricular dysfunction (n=132). Aortic valve replacement (AVR) was evaluated on Perioperative mortality. Aortic valve replacement in patients with LVEF <40% demonstrated low perioperative mortality (2.3%) and favorable long-term overall survival of 55% at 10 years.
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