Age, elevated CRP (OR 1.35), elevated LDL (OR 1.24), coronary artery disease (OR 1.65), smoking (OR 1.34), and hypertension (OR 1.41) significantly increased degenerative valvular heart disease risk.
Established cardiovascular risk factors, including age, hypertension, smoking, and elevated LDL and CRP, are significantly associated with degenerative valvular heart disease in the elderly Chinese population.
Tasa de eventos absoluta: 0% vs 0%
OBJECTIVE: To investigate the prevalence and modifiable risk factors of degenerative valvular heart disease (DVHD) among elderly population in southern China. METHODS: A stratified multistage sampling method was used to recruit subjects. The contents of the survey included the questionnaire, laboratory examination, echocardiography, and other auxiliary examinations. The possible risk factors of DVHD were analyzed by logistic regression analysis. RESULTS: < 0.001). Risk factors associated with DVHD included age (two-fold increased risk for each 10-year increase in age), elevated level C-reactive protein (OR = 1.346, 95% CI: 1.100-1.646), elevated level low density lipoprotein (OR = 1.243, 95% CI: 1.064-1.451), coronary artery disease (OR = 1.651, 95% CI: 1.085-2.513), smoking (OR = 1.341, 95% CI: 1.132-1.589), and hypertension (OR = 1.414, 95% CI: 1.221-1.638). Other significant risk factors included reduced or elevated level red blood cell (OR = 1.347, 95% CI: 1.031-1.761; OR = 1.599, 95% CI: 1.097-2.331; respectively), elevated level platelets (OR = 1.891, 95% CI: 1.118-3.198), elevated level uric acid (OR = 1.282, 95% CI: 1.112-1.479), and stroke (OR: 1.738, 95% CI = 1.085-2.513). CONCLUSIONS: The survey characterized the baseline conditions of DVHD cohort of elderly population in Guangzhou city. The established and emerging risk factors for DVHD may represent challenges and opportunities for therapy.
He et al. (Wed,) reported a other. Age, elevated CRP (OR 1.35), elevated LDL (OR 1.24), coronary artery disease (OR 1.65), smoking (OR 1.34), and hypertension (OR 1.41) significantly increased degenerative valvular heart disease risk.