Key result
Higher preoperative LVEF and lower LV end-systolic dimension index predict reverse remodeling one year post-AVR.
Why the study?
To assess long-term outcomes and investigate factors related to left ventricular reverse remodelling after aortic valve replacement for chronic aortic regurgitation.
What are the long-term outcomes and predictive factors for left ventricular reverse remodelling after aortic valve replacement in patients with chronic aortic regurgitation?
Population
246 patients undergoing AVR for chronic AR at a single institution
Design
Retrospective study
Authors
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Preoperative LVEF and LV end-systolic dimension index may aid selection for AVR in chronic AR; leaves open whether they should guide surgical timing.
Cohort (n=246)
No
What are the long-term outcomes and predictive factors for left ventricular reverse remodelling after aortic valve replacement in patients with chronic aortic regurgitation?
Preoperative LV ejection fraction and LV end-systolic dimension index predict reverse remodelling after AVR for chronic AR, supporting earlier surgical intervention.
Ikuta et al. (2021) conducted a cohort in Chronic aortic regurgitation (n=246). Aortic valve replacement was evaluated on All-cause mortality, cardiac mortality and major adverse cerebral and cardiovascular events. Preoperative LV ejection fraction (OR 1.057; P=0.001) and LV end-systolic dimension index (OR 0.912; P=0.038) significantly predicted reverse remodelling 1 year after aortic valve replacement.
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