Key result
Correcting the Gorlin equation for contraction and pressure recovery improves anatomic AVA correlation to r=0.71.
Why the study?
Does correcting the Gorlin equation for the actual coefficient of contraction and pressure recovery improve its correlation with anatomic aortic area in patients with moderate to severe aortic stenosis?
Population
17 patients with moderate to severe aortic stenosis
Comparison
Assessment of aortic valve area using the Gorlin… vs Assessment of aortic valve area using the…
Design
Cross-sectional
Authors
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Should not yet change aortic stenosis assessment; leaves open prospective validation of corrected Gorlin values.
Observational (n=17)
No
Does correcting the Gorlin equation for the actual coefficient of contraction and pressure recovery improve its correlation with anatomic aortic area in patients with moderate to severe aortic stenosis?
Absolute Event Rate: 0.71% vs 0.23%
p-value: p=<0.001
Correcting the Gorlin equation for the actual coefficient of contraction and pressure recovery significantly improves its correlation with anatomic aortic area in patients with aortic stenosis.
Migliore et al. (2017) conducted an observational in Aortic Stenosis (n=17). Gorlin equation corrected for patient-specific coefficient of contraction and pressure recovery vs. Standard Gorlin equation (coefficient of contraction = 1) was evaluated on Correlation (r) with anatomic aortic valve area by transesophageal echocardiography (p=<0.001). Correcting the Gorlin equation for patient-specific coefficient of contraction and pressure recovery improved its correlation with anatomic aortic valve area from r=0.23 to r=0.71 (P<0.001).
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